Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 12/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.57 |
| ▸ | ATM | Q13315 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135455 | 0.91 | MAPT (0.53) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL10643337 | 0.90 | HTR3E (0.57) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL31411741 | 0.87 | HTR3E (0.51) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL23961208 | 0.85 | GRM3 (0.48) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL2938488 | 0.82 | MAPT (0.44) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL12045685 | 0.82 | ADRB1 (0.46) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL21136655 | 0.82 | SPHK2 (0.50) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL6265075 | 0.81 | LTA4H (0.54) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL6266763 | 0.80 | HRH3 (0.44) | MAPTMAPK1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL25141585 | 0.80 | ALDH1A1 (0.52) | MAPTMAPK1ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371196-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PLATELET AGGREGATION | UNIV MONTREAL (CA) | 2021-10-27 | — | — | EP | disclosed |
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | UNIVERSITE DE MONTREAL (CA) | 2019-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329307-B2 | Heterocyclic compounds as inhibitors of platelet aggregation | F12, F2, F3 | MAPT 1241/4885MAPK1 1667/4885ALDH1A1 1559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.