Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135378 | 0.76 | ALDH1A1 (0.36) | TNKS2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL21135350 | 0.67 | LMNA (0.42) | TNKS2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL18905201 | 0.65 | NLRP3 (0.42) | PIM1TNKS2KDM4EALDH1A1HPGD | |
| SCHEMBL19032599 | 0.63 | NLRP3 (0.38) | PIM1TNKS2KDM4EALDH1A1HPGD | |
| SCHEMBL22652986 | 0.62 | HTR2A (0.39) | TNKS2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL14614362 | 0.61 | HTR2A (0.41) | TNKS2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL29095299 | 0.60 | HTR2A (0.35) | TNKS2KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL24942532 | 0.58 | PIM1 (0.32) | PIM1EGFR | |
| SCHEMBL21882573 | 0.58 | — | — | |
| SCHEMBL22506947 | 0.58 | MEN1 (0.38) | TNKS2KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194464-A1 | MODIFIED DYE COMPOUNDS AND METHODS OF DYEING SUBSTRATES | THE H.D. LEE COMPANY, INC. | 2019-06-27 | — | — | US | disclosed |