Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.36 |
| ▸ | NOS2 | P35228 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | FER | P16591 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21135350 | 0.88 | LMNA (0.42) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 | |
| SCHEMBL21135657 | 0.76 | PIM1 (0.35) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 | |
| SCHEMBL17376745 | 0.72 | CREBBP (0.42) | ALDH1A1TNKS2NOS2KDM4EHPGD | |
| SCHEMBL21135343 | 0.70 | L3MBTL1 (0.41) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 | |
| SCHEMBL19568178 | 0.70 | TSHR (0.50) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 | |
| SCHEMBL6557130 | 0.70 | TSHR (0.50) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 | |
| SCHEMBL21135377 | 0.67 | PARP1 (0.38) | ALDH1A1KDM4EHSD17B10TSHRMAOB | |
| SCHEMBL18905201 | 0.65 | NLRP3 (0.42) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 | |
| SCHEMBL22652986 | 0.64 | HTR2A (0.39) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 | |
| SCHEMBL19032599 | 0.63 | NLRP3 (0.38) | ALDH1A1TNKS2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194464-A1 | MODIFIED DYE COMPOUNDS AND METHODS OF DYEING SUBSTRATES | THE H.D. LEE COMPANY, INC. | 2019-06-27 | — | — | US | disclosed |