Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PIKFYVE | Q9Y2I7 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21055052 | 0.87 | PIKFYVE (0.56) | MAPK1PIKFYVEMEN1KMT2AGAA | |
| SCHEMBL30312554 | 0.87 | PIKFYVE (0.56) | MAPK1PIKFYVEMEN1KMT2AGAA | |
| SCHEMBL21135830 | 0.83 | JAK3 (0.41) | PIKFYVEKDM5AMTORPIK3CAPIK3CB | |
| SCHEMBL21135843 | 0.79 | PIKFYVE (0.43) | NPSR1MAPK1PIKFYVEMEN1KMT2A | |
| SCHEMBL21135844 | 0.76 | PIK3CA (0.42) | PIKFYVEMEN1KMT2AGAAMTOR | |
| SCHEMBL21053972 | 0.74 | PIKFYVE (0.64) | PIKFYVEGAAMTORPIK3CAPIK3CB | |
| SCHEMBL30312484 | 0.74 | PIKFYVE (0.64) | PIKFYVEGAAMTORPIK3CAPIK3CB | |
| SCHEMBL21135798 | 0.74 | PIK3CA (0.41) | MTORPIK3CAPIK3CBALDH1A1PIK3CD | |
| SCHEMBL21135799 | 0.74 | PIK3CA (0.42) | MAPK1ALOX15MTORPIK3CAPIK3CB | |
| SCHEMBL21054603 | 0.73 | PIKFYVE (0.55) | PIKFYVEGAAMTORPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |