Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PIKFYVE | Q9Y2I7 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312488 | 0.86 | PIKFYVE (0.55) | PIK3CAPIKFYVEMTORPIK3CB | |
| SCHEMBL21054603 | 0.86 | PIKFYVE (0.55) | PIK3CAPIKFYVEMTORPIK3CB | |
| SCHEMBL21135838 | 0.83 | TRPM8 (0.42) | ALDH1A1SMN1; SMN2PIK3CAPIKFYVEMTOR | |
| SCHEMBL21135843 | 0.82 | PIKFYVE (0.43) | PIK3CAPIKFYVEPIK3R1MTORPIK3CB | |
| SCHEMBL30312484 | 0.76 | PIKFYVE (0.64) | PIK3CAPIKFYVEMTORPIK3CB | |
| SCHEMBL21053972 | 0.76 | PIKFYVE (0.64) | PIK3CAPIKFYVEMTORPIK3CB | |
| SCHEMBL21135844 | 0.76 | PIK3CA (0.42) | PIK3CALRRK2PIKFYVEPIK3R1MTOR | |
| SCHEMBL21135798 | 0.74 | PIK3CA (0.41) | JAK3ALDH1A1PIK3CALRRK2PIK3R1 | |
| SCHEMBL21135799 | 0.74 | PIK3CA (0.42) | ALDH1A1PIK3CAPIK3R1MTORPIK3CB | |
| SCHEMBL23272141 | 0.72 | PIKFYVE (0.64) | PIK3CAPIKFYVEMTORPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | disclosed |