SCHEMBL21137591

SCHEMBL21137591

C/C=C/CCCC(=O)NC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
CNR1 P21554 4/20 0.41
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
FAAH O00519 2/20 0.40
ALDH1A1 P00352 2/20 0.40
BLM P54132 2/20 0.40
KMT2A Q03164 2/20 0.40
SOAT1 P35610 1/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
APEX1 P27695 1/20 0.40
RECQL P46063 1/20 0.40
PMP22 Q01453 1/20 0.40
GPR18 Q14330 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21137557 1.00 LMNA (0.43) LMNACNR1KDM4EMEN1FAAH
SCHEMBL3347883 1.00 LMNA (0.43) LMNACNR1KDM4EMEN1FAAH
SCHEMBL19300404 0.86
SCHEMBL28340352 0.86
SCHEMBL22294211 0.83 CNR1 (0.57) LMNACNR1KDM4EMEN1FAAH
SCHEMBL22294431 0.83 CNR1 (0.57) LMNACNR1KDM4EMEN1FAAH
SCHEMBL23193125 0.79 TOP1 (0.61) LMNACNR1KDM4EMEN1FAAH
SCHEMBL3080729 0.79
SCHEMBL1041069 0.78 FAAH (0.55) CNR1KDM4EMEN1FAAHALDH1A1
SCHEMBL10112508 0.78 FAAH (0.55) CNR1KDM4EMEN1FAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2023-11-09 US disclosed
EP-3725798-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-10-21 EP disclosed
WO-2019114666-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2019-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357259-A1 BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF DOCK11, PAICS, RHOA LMNA 1356/4885CNR1 2470/4885KDM4E 3886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.