SCHEMBL21137855

SCHEMBL21137855

CCCC(=O)N[C@H]1C(OC(=O)[C@@H](N)Cc2ccccc2)O[C@H](COC(=O)[C@@H](N)Cc2ccccc2)[C@@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.45
▸ KMT2A Q03164 1/20 0.40
▸ MARS1 P56192 3/20 0.39
▸ ANPEP P15144 2/20 0.38
▸ SSTR2 P30874 3/20 0.38
▸ SSTR3 P32745 3/20 0.38
▸ SSTR5 P35346 3/20 0.38
▸ SSTR4 P31391 2/20 0.38
▸ SSTR1 P30872 1/20 0.38
▸ SLC15A1 P46059 1/20 0.37
▸ MCHR1 Q99705 2/20 0.37
▸ IARS1 P41252 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21137857 0.90 HK1 (0.41) LMNAMARS1SSTR4SLC15A1IARS1
Hydrochloric Acid SCHEMBL29777487 0.89 HK1 (0.40) LMNAMARS1SSTR4SLC15A1IARS1
Hydrochloric Acid SCHEMBL21058355 0.89 HK1 (0.40) LMNAMARS1SSTR4SLC15A1IARS1
SCHEMBL6606476 0.77 ALPI (0.44) MARS1SLC15A1
SCHEMBL6588628 0.77 ALPI (0.44) MARS1SLC15A1
SCHEMBL21058353 0.74 ACE (0.48) KMT2A
SCHEMBL15150246 0.72 ALPI (0.47) MARS1SLC15A1IARS1
Hydrochloric Acid SCHEMBL31353001 0.72 PYGB (0.38) LMNA
SCHEMBL21058378 0.72 CA1 (0.48) SSTR2SSTR3SSTR5SSTR4SSTR1
SCHEMBL21137858 0.71 CYP3A4 (0.42) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA LMNA 2632/4885KMT2A 4314/4885MARS1 4417/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA LMNA 2632/4885KMT2A 4314/4885MARS1 4417/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA LMNA 2743/4885KMT2A 4171/4885MARS1 4278/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA LMNA 2743/4885KMT2A 4171/4885MARS1 4278/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA LMNA 2743/4885KMT2A 4171/4885MARS1 4278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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