SCHEMBL21137857

SCHEMBL21137857

CCCC(=O)N[C@H]1C(O)O[C@H](COC(=O)[C@@H](N)Cc2ccccc2)[C@@H](O)[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HK1 P19367 2/20 0.41
▸ HK2 P52789 2/20 0.41
▸ LMNA P02545 1/20 0.39
▸ SLC15A1 P46059 1/20 0.38
▸ ALPI P09923 1/20 0.38
▸ PKM P14618 1/20 0.38
▸ PTGS1 P23219 1/20 0.38
▸ XIAP P98170 1/20 0.38
▸ SLC7A5 Q01650 1/20 0.38
▸ MARS1 P56192 3/20 0.37
▸ DAGLA Q9Y4D2 1/20 0.37
▸ SSTR4 P31391 1/20 0.36
▸ IARS1 P41252 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL21058355 0.99 HK1 (0.40) HK1HK2LMNASLC15A1ALPI
Hydrochloric Acid SCHEMBL29777487 0.99 HK1 (0.40) HK1HK2LMNASLC15A1ALPI
SCHEMBL21137855 0.90 LMNA (0.45) LMNASLC15A1MARS1SSTR4IARS1
SCHEMBL21058353 0.82 ACE (0.48) —
Hydrochloric Acid SCHEMBL31353002 0.81 PYGB (0.41) HK1HK2LMNAIARS1
Hydrochloric Acid SCHEMBL31353001 0.81 PYGB (0.38) HK1HK2LMNA
SCHEMBL21137858 0.81 CYP3A4 (0.42) SLC7A5
SCHEMBL28503463 0.80 HK1 (0.46) HK1HK2SSTR4
Hydrochloric Acid SCHEMBL21058350 0.80 SLC15A1 (0.33) HK1HK2SLC15A1MARS1IARS1
Hydrochloric Acid SCHEMBL29777465 0.80 SLC15A1 (0.33) HK1HK2SLC15A1MARS1IARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA HK1 111/4885HK2 218/4885LMNA 2632/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA HK1 111/4885HK2 218/4885LMNA 2632/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA HK1 83/4885HK2 141/4885LMNA 2743/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA HK1 83/4885HK2 141/4885LMNA 2743/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA HK1 83/4885HK2 141/4885LMNA 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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