Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CTSC | P53634 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21144700 | 1.00 | ADRB2 (0.36) | ADRB2ADRB1PDE4APDE4BPDE4C | |
| SCHEMBL18930224 | 0.77 | ADRB2 (0.39) | ADRB2ADRB1EGLN2TRPV3S1PR1 | |
| Hydrochloric Acid SCHEMBL21144846 | 0.76 | ADRB2 (0.39) | ADRB2ADRB1EGLN2TRPV3S1PR1 | |
| Hydrochloric Acid SCHEMBL21144843 | 0.76 | ADRB2 (0.39) | ADRB2ADRB1EGLN2TRPV3S1PR1 | |
| SCHEMBL21596899 | 0.74 | TRPV4 (0.41) | ADRB2ADRB1PDE4APDE4BPDE4C | |
| SCHEMBL21144944 | 0.74 | CYP3A4 (0.42) | S1PR3FFAR1CYP3A4MAPK1 | |
| SCHEMBL18920544 | 0.74 | CYP3A4 (0.42) | S1PR3FFAR1CYP3A4MAPK1 | |
| SCHEMBL12763649 | 0.72 | TRPV4 (0.42) | PDE4APDE4BPDE4CPDE4DEGLN2 | |
| SCHEMBL16109779 | 0.71 | MAPT (0.39) | PDE4APDE4BPDE4CPDE4DEGLN2 | |
| SCHEMBL23357236 | 0.71 | CYP3A4 (0.35) | CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654818-B2 | Furane derivatives as inhibitors of ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-05-19 | — | — | US | disclosed |
| US-20190218196-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218196-A1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | ATAD2, ATAD2B, TAF1L | ADRB2 3138/4885ADRB1 2912/4885PDE4A 2187/4885 |
| US-10654818-B2 | Furane derivatives as inhibitors of ATAD2 | ATAD2, ATAD2B, TAF1L | ADRB2 3138/4885ADRB1 2912/4885PDE4A 2187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.