Cadaverine Tartrate

Cadaverine Tartrate

SCHEMBL21145109

CC(C)NC(C)C.O=C(O)C(O)C(O)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.37
TSHR P16473 5/20 0.59
TP53 P04637 2/20 0.47
TDP1 Q9NUW8 4/20 0.47
NFKB1 P19838 2/20 0.41
CYP2C19 P33261 1/20 0.41
BLM P54132 3/20 0.37
KDM4E B2RXH2 2/20 0.37
POLB P06746 2/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 2/20 0.37
CYP3A4 P08684 2/20 0.37
PMP22 Q01453 2/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
CYP1A2 P05177 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cadaverine Tartrate SCHEMBL21145107 1.00 TSHR (0.59) TSHRTP53TDP1NFKB1CYP2C19
Lactic Acid SCHEMBL5671703 0.85 TP53 (0.69) TSHRTP53TDP1CYP2C19LMNA
Cadaverine Tartrate SCHEMBL1835488 0.82 TSHR (0.59) TSHRTP53TDP1NFKB1CYP2C19
Lactic Acid SCHEMBL2800615 0.82 TP53 (0.65) TSHRTP53TDP1CYP2C19LMNA
Lactic Acid SCHEMBL216432 0.82 TP53 (0.65) TSHRTP53TDP1CYP2C19LMNA
SCHEMBL19091353 0.81 TSHR (0.43) TSHRTP53TDP1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL8944188 0.81 TSHR (0.77) TSHRTP53NFKB1CYP2C19LMNA
Tartaric Acid SCHEMBL30100371 0.81 TSHR (0.77) TSHRTP53NFKB1CYP2C19LMNA
Bicarbonate SCHEMBL8871100 0.81 TDP1 (0.61) TSHRTP53TDP1CYP2C19LMNA
Cadaverine Tartrate SCHEMBL7209361 0.78 TSHR (0.71) TSHRTP53NFKB1CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
EP-3518878-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION Henkel AG & Co. KGaA (DE) 2019-08-07 EP disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 ADRB2 2243/4885TSHR 3146/4885TP53 2105/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK ADRB2 1303/4885TSHR 1850/4885TP53 2548/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA ADRB2 3747/4885TSHR 3345/4885TP53 1209/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 ADRB2 2259/4885TSHR 2235/4885TP53 1442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.