Pyruvate

Pyruvate

SCHEMBL21145127

CC(=O)C(=O)O.CCCN

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.39
FFAR3 O14843 3/20 0.38
HDAC1 Q13547 3/20 0.38
HDAC2 Q92769 3/20 0.38
HDAC3 O15379 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
CES1 P23141 2/20 0.38
TDP1 Q9NUW8 2/20 0.37
GLRA1 P23415 1/20 0.37
SLC6A9 P48067 1/20 0.37
OR51E2 Q9H255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GABRR1 P24046 3/20 0.36
PAOX Q6QHF9 2/20 0.36
TSHR P16473 2/20 0.35
THPO P40225 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
THRB P10828 2/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL29827134 0.87 FFAR3 (0.50) ALOX15FFAR3HDAC1HDAC2HDAC3
Oxalic Acid SCHEMBL27329110 0.87 ALOX15 (0.48) ALOX15FFAR3HDAC1HDAC2HDAC3
Pyruvate SCHEMBL21145119 0.87
Acetic Acid SCHEMBL25215621 0.87 FFAR3 (0.50) ALOX15FFAR3HDAC1HDAC2HDAC3
Oxalic Acid SCHEMBL10594746 0.87 ALOX15 (0.48) ALOX15FFAR3HDAC1HDAC2HDAC3
Acetic Acid SCHEMBL25240316 0.87 FFAR3 (0.50) ALOX15FFAR3HDAC1HDAC2HDAC3
Acetic Acid SCHEMBL1807476 0.87
Oxalic Acid SCHEMBL2110681 0.87 ALOX15 (0.48) ALOX15FFAR3HDAC1HDAC2HDAC3
Acetic Acid SCHEMBL11455480 0.84
Acetic Acid SCHEMBL11473957 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 ALOX15 4377/4885FFAR3 2270/4885HDAC1 121/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK ALOX15 3791/4885FFAR3 1837/4885HDAC1 193/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA ALOX15 4554/4885FFAR3 3218/4885HDAC1 116/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 ALOX15 4303/4885FFAR3 2914/4885HDAC1 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.