Diphenylamine

Diphenylamine

SCHEMBL21145273

CCC(=O)O.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 12/20 0.68
GAA P10253 5/20 0.68
ALDH1A1 P00352 5/20 0.58
HPGD P15428 4/20 0.58
HSD17B10 Q99714 3/20 0.57
POLB P06746 1/20 0.57
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
CASP3 P42574 1/20 0.56
SENP7 Q9BQF6 1/20 0.56
PTPN7 P35236 1/20 0.55
PTPN12 Q05209 1/20 0.55
MAPK1 P28482 3/20 0.55
ALOX12 P18054 2/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
PTGS1 P23219 1/20 0.55
SLC6A2 P23975 1/20 0.55
PTGS2 P35354 1/20 0.55
HTR2B P41595 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL27671181 0.88 MAPT (0.66) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylamine SCHEMBL27513063 0.85 HSD17B10 (0.63) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylamine SCHEMBL21145240 0.85 MAPT (0.68) MAPTGAAALDH1A1HPGDHSD17B10
Propionic Acid SCHEMBL11038238 0.84 GAA (0.50) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylamine SCHEMBL21145190 0.83 HSD17B10 (0.60) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylamine SCHEMBL374606 0.82 MAPT (0.71) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylamine SCHEMBL28553827 0.82 MAPT (0.71) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylamine SCHEMBL9332947 0.82 HSD17B10 (0.67) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylamine SCHEMBL6904395 0.82 MAPT (0.71) MAPTGAAALDH1A1HPGDHSD17B10
Diphenylurea SCHEMBL29504221 0.82 EPHX1 (0.74) MAPTGAAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 MAPT 388/4885GAA 3537/4885ALDH1A1 1010/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK MAPT 3322/4885GAA 4733/4885ALDH1A1 3629/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA MAPT 622/4885GAA 3281/4885ALDH1A1 1465/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 MAPT 285/4885GAA 3616/4885ALDH1A1 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.