Diphenylamine

Diphenylamine

SCHEMBL21145240

CCCC(=O)O.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.68
ALDH1A1 P00352 5/20 0.68
HPGD P15428 4/20 0.68
GAA P10253 2/20 0.56
ALOX5 P09917 1/20 0.56
HDAC3 O15379 2/20 0.54
HDAC1 Q13547 2/20 0.54
HDAC2 Q92769 2/20 0.54
HDAC8 Q9BY41 2/20 0.54
FFAR3 O14843 1/20 0.54
POLB P06746 1/20 0.52
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
CYP2C19 P33261 1/20 0.51
RECQL P46063 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HSD17B10 Q99714 3/20 0.50
PTPN7 P35236 1/20 0.50
PTPN12 Q05209 1/20 0.50
CASP3 P42574 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL21145098 0.88 ALDH1A1 (0.59) MAPTALDH1A1HPGDGAAALOX5
Diphenylamine SCHEMBL21145171 0.86 AKR1B1 (0.59) MAPTALDH1A1HPGDGAAMEN1
Diphenylamine SCHEMBL21145136 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A
Diphenylamine SCHEMBL21145188 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A
Palmitic Acid SCHEMBL9330998 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A
Diphenylamine SCHEMBL21145265 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A
Dodecanoate SCHEMBL21145309 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A
Diphenylamine SCHEMBL21145245 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A
Undecanoate SCHEMBL21145103 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A
Stearic Acid SCHEMBL28277833 0.85 GPR84 (0.61) MAPTALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 MAPT 388/4885ALDH1A1 1010/4885HPGD 2076/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK MAPT 3322/4885ALDH1A1 3629/4885HPGD 634/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA MAPT 622/4885ALDH1A1 1465/4885HPGD 3201/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 MAPT 285/4885ALDH1A1 1179/4885HPGD 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.