Diphenylamine

Diphenylamine

SCHEMBL21145296

CC(=O)C(=O)O.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.65
POLB P06746 1/20 0.65
HSD17B10 Q99714 3/20 0.60
ALDH1A1 P00352 5/20 0.59
GAA P10253 4/20 0.59
HSP90AA1 P07900 1/20 0.59
CASP3 P42574 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
TSHR P16473 2/20 0.57
ALOX12 P18054 2/20 0.57
MAPK1 P28482 2/20 0.57
ALOX15 P16050 1/20 0.57
PTGS1 P23219 1/20 0.57
SLC6A2 P23975 1/20 0.57
PTGS2 P35354 1/20 0.57
HTR2B P41595 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
NAPRT Q6XQN6 1/20 0.56
MAPK13 O15264 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL374606 0.90 MAPT (0.71) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL28553827 0.90 MAPT (0.71) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL6904395 0.90 MAPT (0.71) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL29736617 0.87 HSD17B10 (0.71) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL21145247 0.87 HSD17B10 (0.71) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL21145246 0.87 HSD17B10 (0.71) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL29875738 0.86 MAPT (0.61) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL8610102 0.85 MAPT (0.65) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL28205265 0.84 HSD17B10 (0.75) MAPTPOLBHSD17B10ALDH1A1GAA
Diphenylamine SCHEMBL9348368 0.84 HSD17B10 (0.75) MAPTPOLBHSD17B10ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 MAPT 388/4885POLB 1221/4885HSD17B10 1729/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK MAPT 3322/4885POLB 702/4885HSD17B10 1655/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA MAPT 622/4885POLB 932/4885HSD17B10 3206/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 MAPT 285/4885POLB 598/4885HSD17B10 2030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.