Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2114582 | 0.85 | CNR2 (0.36) | ALDH1A1LMNACYP17A1CNR2MEN1 | |
| Hydrochloric Acid SCHEMBL2114509 | 0.79 | LMNA (0.37) | ALDH1A1LMNAP2RX7CYP17A1CNR2 | |
| Hydrochloric Acid SCHEMBL2116036 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAP2RX7CYP17A1CNR2 | |
| Hydrochloric Acid SCHEMBL2115079 | 0.74 | NPSR1 (0.34) | ALDH1A1LMNAP2RX7MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9065946 | 0.71 | ALDH1A1 (0.42) | ALDH1A1LMNAP2RX7CYP17A1CNR2 | |
| Hydrochloric Acid SCHEMBL2114763 | 0.68 | LMNA (0.37) | ALDH1A1LMNAP2RX7CYP17A1CNR2 | |
| Hydrochloric Acid SCHEMBL2117142 | 0.66 | EPHX2 (0.39) | ALDH1A1LMNACNR2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2119032 | 0.66 | GLA (0.36) | ALDH1A1LMNACYP17A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL217485 | 0.65 | ALDH1A1 (0.30) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL2114200 | 0.64 | LMNA (0.38) | ALDH1A1LMNAP2RX7CYP17A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | claimed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | claimed |
| US-8957159-B2 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-02-17 | — | — | US | disclosed |
| US-20140066567-A1 | Multiple Catalyst System for Olefin Polymerization and Polymers Produced Therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2014-03-06 | — | — | US | disclosed |
| US-8563647-B2 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120095157-A1 | Multiple Catalyst System For Olefin Polymerization And Polymers Produced Therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-04-19 | — | — | US | disclosed |
| US-8071687-B2 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-20090069475-A1 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-03-12 | — | — | US | disclosed |
| US-20070293640-A1 | Multiple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-12-20 | — | — | US | disclosed |
| US-7294681-B2 | Mutliple catalyst system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-7223822-B2 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20040220359-A1 | Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-11-04 | — | — | US | disclosed |
| US-6423793-B1 | THERMOPLASTIC ELASTOMERS | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-07-23 | — | — | US | disclosed |