SCHEMBL21147112

SCHEMBL21147112

Cc1ccc(N(C)c2ccccc2)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.43
FTO Q9C0B1 1/20 0.39
CXCR2 P25025 2/20 0.38
TP53 P04637 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 2/20 0.37
SLC6A2 P23975 2/20 0.37
CHRM1 P11229 1/20 0.37
ADRA1A P35348 1/20 0.37
HTR2B P41595 1/20 0.37
HSP90AA1 P07900 2/20 0.36
HSP90AB1 P08238 1/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
CSNK2A1 P68400 1/20 0.36
MAPT P10636 1/20 0.36
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15463290 0.87 TRPA1 (0.42) TRPA1SLC6A2MAPTSLC6A4
SCHEMBL13509013 0.81 MEN1 (0.40) TP53TDP1LMNASLC6A2MEN1
SCHEMBL6877796 0.78 CXCR2 (0.47) CXCR2TDP1LMNAHSP90AA1HSP90AB1
SCHEMBL28286414 0.77 CSNK2A1 (0.49) HSP90AA1HSP90AB1MEN1KMT2ACSNK2A1
SCHEMBL4425864 0.77 MEN1 (0.40) TDP1LMNAMEN1KMT2ACA12
SCHEMBL6878929 0.77 ALDH1A1 (0.43) CXCR2TP53TDP1LMNAMEN1
SCHEMBL6875951 0.76 ACHE (0.41) CXCR2TDP1LMNASLC6A2HTR2B
SCHEMBL28330493 0.76 HDAC7 (0.41) LMNACHRM1MEN1KMT2AMAPT
Bromide SCHEMBL10436173 0.76 CXCR2 (0.46) CXCR2TDP1LMNAHSP90AA1HSP90AB1
SCHEMBL12401692 0.76 TRPA1 (0.54) TRPA1TP53TDP1LMNASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2692796-B1 COMPOSITION SUMITOMO CHEMICAL CO (JP) 2019-07-10 EP disclosed