Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | TFEB | P19484 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199476 | 0.84 | ELANE (0.61) | ELANEMEN1KMT2AMAPTLMNA | |
| SCHEMBL14775180 | 0.82 | NFE2L2 (0.49) | MEN1KMT2ANFE2L2TFEBKDM4E | |
| SCHEMBL14775179 | 0.82 | NFE2L2 (0.49) | MEN1KMT2ANFE2L2TFEBKDM4E | |
| SCHEMBL141456 | 0.81 | ELANE (0.57) | ELANEKMT2AMAPTLMNANPSR1 | |
| SCHEMBL14775182 | 0.81 | MEN1 (0.50) | MEN1KMT2ANFE2L2TFEBKDM4E | |
| SCHEMBL12379239 | 0.81 | MEN1 (0.52) | MEN1KMT2ANFE2L2TFEBKDM4E | |
| SCHEMBL8291205 | 0.81 | MEN1 (0.52) | MEN1KMT2ANFE2L2TFEBKDM4E | |
| SCHEMBL29607284 | 0.80 | ELANE (0.74) | ELANEMAPTLMNANPSR1 | |
| SCHEMBL28212448 | 0.77 | THRB (0.48) | MEN1KMT2ANFE2L2TFEBKDM4E | |
| SCHEMBL28212445 | 0.77 | KDM4E (0.46) | ELANEMEN1KMT2ANFE2L2TFEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209604-A1 | OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209604-A1 | OLIGONUCLEOTIDES, COMPOSITIONS AND METHODS THEREOF | TLR9, RNGTT, NT5C3B | ELANE 1670/4885MEN1 4562/4885KMT2A 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.