Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.58 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30743526 | 0.87 | ALDH3A1 (0.53) | METNOD1CXCL8ALDH1A1LMNA | |
| SCHEMBL21295049 | 0.80 | MET (0.52) | METNOD1CXCL8RECQLALDH1A1 | |
| SCHEMBL29847207 | 0.80 | MET (0.52) | METNOD1CXCL8RECQLALDH1A1 | |
| SCHEMBL29953394 | 0.77 | NOD1 (0.38) | METNOD1CXCL8RECQLALDH1A1 | |
| SCHEMBL1773438 | 0.77 | CYP2C19 (0.55) | METNOD1CXCL8RECQLALDH1A1 | |
| SCHEMBL7014825 | 0.76 | CA12 (0.55) | METNOD1CXCL8RECQLALDH1A1 | |
| SCHEMBL17714324 | 0.75 | NOD1 (0.42) | METNOD1CXCL8RECQLALDH1A1 | |
| SCHEMBL3705420 | 0.74 | MET (1.00) | METALDH1A1LMNACYP2C19ALDH3A1 | |
| SCHEMBL29847431 | 0.74 | MET (1.00) | METALDH1A1LMNACYP2C19ALDH3A1 | |
| SCHEMBL21115189 | 0.72 | HTR6 (0.44) | METNOD1CXCL8RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10906900-B2 | Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-02-02 | — | — | US | disclosed |
| US-20190211011-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906900-B2 | Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases | PSEN2, CLN6, MAPT | MET 4720/4885NOD1 3164/4885CXCL8 4277/4885 |
| US-20190211011-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | PSEN2, SNCA, MAPT | MET 4686/4885NOD1 3184/4885CXCL8 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.