SCHEMBL21148463

SCHEMBL21148463

c1ccc2cc(-c3nc(-c4ccc(-c5cccc6ccccc56)cc4)nc(-c4ccc(-c5cccc6oc7ccccc7c56)cc4)n3)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.40
ENPP1 P22413 2/20 0.40
ENPP3 O14638 1/20 0.40
ALDH1A1 P00352 7/20 0.40
HSD17B10 Q99714 6/20 0.40
KDM4E B2RXH2 5/20 0.40
MAPT P10636 5/20 0.40
HPGD P15428 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 2/20 0.40
TP53 P04637 2/20 0.40
MAPK1 P28482 2/20 0.40
TSHR P16473 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24656724 0.99 PIM1 (0.39) PIM1ENPP1ENPP3ALDH1A1HSD17B10
SCHEMBL24314664 0.97 PIM1 (0.39) PIM1ENPP1ENPP3ALDH1A1HSD17B10
SCHEMBL21148510 0.96 ALDH1A1 (0.40) PIM1ENPP1ENPP3ALDH1A1HSD17B10
SCHEMBL23822808 0.96 PIM1 (0.39) PIM1ENPP1ENPP3ALDH1A1HSD17B10
SCHEMBL23385015 0.96 ALDH1A1 (0.40) PIM1ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL21148591 0.96 ALDH1A1 (0.40) PIM1ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL24655023 0.95 ALDH1A1 (0.44) PIM1ENPP1ENPP3ALDH1A1HSD17B10
SCHEMBL23821826 0.94 HCRTR1 (0.39) PIM1ENPP1ENPP3ALDH1A1HSD17B10
SCHEMBL23820722 0.94 PIM1 (0.40) PIM1ENPP1ENPP3ALDH1A1HSD17B10
SCHEMBL23821765 0.94 ALDH1A1 (0.43) PIM1ENPP1ENPP3ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4276924-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-11-15 EP disclosed
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-11-02 US disclosed
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-11-02 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
EP-4258372-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-10-11 EP disclosed
EP-4254527-A1 ORGANIC LIGHT EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-10-04 EP disclosed
EP-4243100-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
EP-4235829-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed
EP-4235830-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-08-30 EP disclosed
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed
WO-2023287228-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2023-01-19 WO disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PIM1 3381/4885ENPP1 1142/4885ENPP3 1810/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 PIM1 3381/4885ENPP1 1142/4885ENPP3 1810/4885
US-20230354706-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, PER2 PIM1 2638/4885ENPP1 1710/4885ENPP3 3094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.