SCHEMBL21150166

SCHEMBL21150166

C=Cc1cc2c(cc1/C=C\C)oc1ccc(-c3c4ccccc4c(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)c4ccccc34)cc12

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 3/20 0.33
▸ PLA2G4A P47712 3/20 0.33
▸ PLA2G10 O15496 1/20 0.32
▸ PTPN1 P18031 2/20 0.30
▸ PTPN2 P17706 1/20 0.30
▸ MMP12 P39900 1/20 0.30
▸ MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20416908 0.95 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10PTPN1PTPN2
SCHEMBL21169833 0.94 PLA2G2A (0.36) PLA2G2APLA2G4APLA2G10PTPN1PTPN2
SCHEMBL23919645 0.94 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10
SCHEMBL21923886 0.94 PLA2G2A (0.33) PLA2G2APLA2G4APLA2G10
SCHEMBL21127448 0.93 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10PTPN1PTPN2
SCHEMBL23849346 0.93 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10PTPN1PTPN2
SCHEMBL23060310 0.93 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10PTPN1PTPN2
SCHEMBL23109594 0.92 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10PTPN1PTPN2
SCHEMBL24208533 0.90 MMP12 (0.35) PLA2G2APLA2G4APLA2G10MMP12MMP13
SCHEMBL24119038 0.88 MMP12 (0.35) MMP12MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11139437-B2 Compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2021-10-05 — — US disclosed
US-20190214579-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-07-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11139437-B2 Compound and organic electroluminescence device RIF1, OR10J3, LEF1 PLA2G2A 4600/4885PLA2G4A 4851/4885PLA2G10 4595/4885
US-20190214579-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, RIF1, OR10J3 PLA2G2A 4468/4885PLA2G4A 4828/4885PLA2G10 4488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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