Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21151890 | 0.81 | KMT2A (0.36) | KDM4EKMT2AOPRM1 | |
| SCHEMBL21152096 | 0.80 | OPRM1 (0.43) | KDM4EKMT2AOPRM1 | |
| SCHEMBL21150835 | 0.63 | NR1H2 (0.39) | KMT2A | |
| SCHEMBL11114336 | 0.60 | KMT2A (0.42) | KDM4EKMT2AOPRM1 | |
| SCHEMBL21150818 | 0.59 | TSHR (0.44) | KDM4EKMT2A | |
| SCHEMBL18012255 | 0.57 | KDM4E (0.64) | KDM4EKMT2A | |
| SCHEMBL807124 | 0.57 | KDM4E (1.00) | KDM4EKMT2A | |
| SCHEMBL10500770 | 0.56 | KMT2A (0.46) | KDM4EKMT2A | |
| SCHEMBL16750982 | 0.56 | KDM4E (0.69) | KDM4EKMT2AOPRM1 | |
| SCHEMBL10499852 | 0.56 | CYP1A2 (0.54) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |