Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21150818 | 0.88 | TSHR (0.44) | USP30GPR119TSHRMEN1KMT2A | |
| SCHEMBL21150851 | 0.85 | GPR119 (0.39) | HDAC2HDAC1USP30GPR119TSHR | |
| SCHEMBL4224081 | 0.74 | GPR119 (0.45) | NR1H2PARP14USP30GPR119KDM1A | |
| SCHEMBL4220685 | 0.71 | NR1H4 (0.37) | NR1H2GPR119MEN1KMT2A | |
| SCHEMBL521464 | 0.70 | NR1H2 (0.48) | NR1H2HDAC2HDAC1USP30GPR119 | |
| SCHEMBL14346584 | 0.70 | ALDH1A1 (0.39) | GPR119TSHRALOX15NAMPT | |
| SCHEMBL21152108 | 0.69 | POLB (0.34) | — | |
| SCHEMBL4443471 | 0.69 | USP2 (0.46) | HDAC2HDAC1GPR119TSHRKMT2A | |
| SCHEMBL17153057 | 0.68 | NR1H2 (0.46) | NR1H2USP30GPR119KDM1ANAMPT | |
| SCHEMBL30198151 | 0.67 | GPR119 (0.60) | NR1H2USP30GPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |