Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21151890 | 0.83 | KMT2A (0.36) | OPRM1KMT2AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL21151155 | 0.80 | KDM4E (0.36) | OPRM1KMT2AKDM4E | |
| SCHEMBL21150818 | 0.75 | TSHR (0.44) | KMT2AKDM4EMEN1OPRD1OPRK1 | |
| SCHEMBL7668013 | 0.70 | SIGMAR1 (0.50) | KMT2APOLBALDH1A1 | |
| SCHEMBL10499852 | 0.70 | CYP1A2 (0.54) | KMT2AKDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL21152108 | 0.69 | POLB (0.34) | KDM4EPOLB | |
| SCHEMBL13451571 | 0.69 | OPRM1 (0.44) | OPRM1KMT2ACYP1A2CYP2D6CYP3A4 | |
| SCHEMBL16750982 | 0.68 | KDM4E (0.69) | OPRM1KMT2AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL6639926 | 0.68 | LMNA (0.40) | KMT2ACYP3A4MEN1ALDH1A1 | |
| SCHEMBL6010129 | 0.67 | SMN1; SMN2 (0.49) | OPRM1KMT2AKDM4EMEN1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136442-A1 | CD16A BINDING AGENTS AND USES THEREOF | KLEO PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |