SCHEMBL21151545

SCHEMBL21151545

N#Cc1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc5c4-c4ccccc4C54c5ccccc5Oc5ccccc54)n3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 12/20 0.37
ABCB1 P08183 7/20 0.37
HTT P42858 1/20 0.36
PDK2 Q15119 1/20 0.34
ABCC1 P33527 3/20 0.34
MYC P01106 1/20 0.34
ALDH1A3 P47895 1/20 0.33
OPRD1 P41143 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
KAT6A Q92794 1/20 0.32
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22908161 0.99 ABCG2 (0.38) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL21151547 0.96 ABCG2 (0.37) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL21151546 0.96 ABCG2 (0.37) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL21343706 0.94 ABCG2 (0.37) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL24905526 0.94 ABCG2 (0.37) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL21701688 0.94 ABCG2 (0.37) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL23256520 0.93 ABCG2 (0.34) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL22908160 0.93 PDK2 (0.40) ABCG2HTTPDK2ALDH1A3GABRA1
SCHEMBL21701684 0.92 ABCG2 (0.38) ABCG2ABCB1HTTPDK2ABCC1
SCHEMBL21343151 0.92 ABCG2 (0.34) ABCG2ABCB1HTTPDK2ABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11542258-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-01-03 US disclosed
US-20210217967-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-07-15 US disclosed
US-20200262825-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2020-08-20 US disclosed
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE PPOX, ERO1A, HMOX2 ABCG2 3903/4885ABCB1 1123/4885HTT 33/4885
US-20200262825-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY1, CYP1A1, CYP1B1 ABCG2 1542/4885ABCB1 850/4885HTT 3350/4885
US-11542258-B2 Heterocyclic compound and organic light emitting device comprising the same CYP1A1, CRY1, CYP1B1 ABCG2 1229/4885ABCB1 579/4885HTT 2643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.