Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PNLIP | P16233 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460094 | 0.81 | PRSS1 (0.57) | ALDH1A1PRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL29287102 | 0.79 | PRSS1 (0.59) | ALDH1A1PRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL23040636 | 0.79 | PRSS1 (0.59) | ALDH1A1PRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL678739 | 0.78 | ALDH1A1 (0.62) | ALDH1A1PRKCAPRKCDPRSS1PRSS2 | |
| SCHEMBL28318971 | 0.78 | ALDH1A1 (0.49) | ALDH1A1PRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL28320083 | 0.78 | ALDH1A1 (0.52) | ALDH1A1PRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL21151713 | 0.77 | PRKCA (0.41) | ALDH1A1PRKCAPRKCDPRSS1PRSS2 | |
| SCHEMBL9963977 | 0.77 | ALDH1A1 (0.46) | ALDH1A1PRSS1PRSS2PRSS3CYP3A4 | |
| SCHEMBL339893 | 0.77 | ALDH1A1 (0.65) | ALDH1A1PRKCAPRKCDPRSS1PRSS2 | |
| SCHEMBL2696844 | 0.77 | ALDH1A1 (0.65) | ALDH1A1PRKCAPRKCDPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858334-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190210993-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10858334-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | PPOX, TST, COX6C | ALDH1A1 613/4885PRKCA 3769/4885PRKCD 4044/4885 |
| US-20190210993-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | PPOX, TST, COX6C | ALDH1A1 613/4885PRKCA 3769/4885PRKCD 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.