Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387242 | 1.00 | PPARG (0.47) | PPARGPPARDPPARAESR1ALDH1A1 | |
| SCHEMBL211526 | 0.89 | PPARG (0.40) | PPARGPPARDPPARAESR1ALDH1A1 | |
| SCHEMBL8390279 | 0.83 | MIF (0.54) | ALDH1A1GAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL8387418 | 0.83 | HPGD (0.44) | GAAHPGDSMN1; SMN2LMNANPSR1 | |
| SCHEMBL8390281 | 0.83 | MIF (0.54) | ALDH1A1GAAHPGDSMN1; SMN2LMNA | |
| SCHEMBL8387413 | 0.83 | HPGD (0.44) | GAAHPGDSMN1; SMN2LMNANPSR1 | |
| SCHEMBL4839224 | 0.80 | ALDH1A1 (0.61) | PPARGPPARDPPARAALDH1A1KDM4E | |
| SCHEMBL4839242 | 0.80 | ALDH1A1 (0.61) | PPARGPPARDPPARAALDH1A1KDM4E | |
| SCHEMBL3785276 | 0.79 | THRB (0.57) | ESR1ALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL3785272 | 0.79 | THRB (0.57) | ESR1ALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998563-A | POLYSILOXANE MODIFIED WITH A CINNAMOYL GROUP | LG ELECTRONICS INC. (KR) | 1999-12-07 | — | — | US | disclosed |
| US-5824377-A | POLYSILOXANE HAVING PENDANT CINNAMOYL GROUP | LG ELECTRONICS INC. (KR) | 1998-10-20 | — | — | US | disclosed |