Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | MMP1 | P03956 | 5/20 | 0.40 |
| ▸ | MMP3 | P08254 | 5/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 4/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19786581 | 0.81 | ALDH1A1 (0.41) | MMP2MMP1MMP3MMEALDH1A1 | |
| SCHEMBL19575792 | 0.81 | ALDH1A1 (0.41) | MMP2MMP1MMP3MMEALDH1A1 | |
| SCHEMBL24591967 | 0.80 | MMP1 (0.43) | MMP2MMP1MMP3TNFADAM17 | |
| SCHEMBL684796 | 0.75 | ALDH1A1 (0.42) | MMP2MMP1MMP3ALDH1A1MMP9 | |
| SCHEMBL12401342 | 0.75 | ALDH1A1 (0.62) | MMP2MMP1MMP3ADAM17ALDH1A1 | |
| SCHEMBL684233 | 0.75 | ALDH1A1 (0.42) | MMP2MMP1MMP3ALDH1A1MMP9 | |
| SCHEMBL13223906 | 0.73 | CTSL (0.44) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL13223901 | 0.73 | CTSL (0.44) | ALDH1A1CTSLCTSBCTSSCTSK | |
| SCHEMBL13034061 | 0.72 | CTSL (0.36) | MMP2MMP1MMP3ALDH1A1MMP9 | |
| SCHEMBL12191402 | 0.71 | ALDH1A1 (0.41) | MMP2MMP1MMP3ALDH1A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209702-A1 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209702-A1 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | SERPINA6, NR3C1, NR3C2 | MMP2 3878/4885MMP1 3724/4885MMP3 2441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.