Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19348082 | 0.83 | ALDH1A1 (0.49) | MAPTCDK4 | |
| SCHEMBL4065096 | 0.83 | WNT3A (0.55) | WNT3AMEN1MAPTKMT2A | |
| SCHEMBL18453164 | 0.80 | WNT3A (0.53) | WNT3AMEN1MAPTKMT2ACASP6 | |
| SCHEMBL4072437 | 0.80 | MAPT (0.49) | MAPTCDK4 | |
| SCHEMBL27057782 | 0.80 | WNT3A (0.47) | WNT3AMAPTGFERCDK4 | |
| SCHEMBL22413899 | 0.79 | CDK4 (0.57) | WNT3ACDK4 | |
| SCHEMBL2069135 | 0.79 | CASP6 (0.53) | WNT3AMEN1MAPTKMT2ACASP6 | |
| SCHEMBL23444034 | 0.79 | MAPT (0.68) | MEN1MAPTKMT2ACASP6GFER | |
| SCHEMBL13616130 | 0.77 | CASP6 (0.57) | WNT3AMEN1MAPTKMT2ACASP6 | |
| SCHEMBL29557360 | 0.76 | WNT3A (0.50) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204378-B3 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2022-05-25 | — | — | EP | disclosed |
| EP-3204378-B1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2019-07-10 | — | — | EP | disclosed |