⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267090 | 0.73 | — | — | |
| SCHEMBL9735156 | 0.71 | — | — | |
| SCHEMBL19805377 | 0.68 | — | — | |
| SCHEMBL16709916 | 0.68 | — | — | |
| SCHEMBL12778665 | 0.67 | — | — | |
| SCHEMBL9531057 | 0.67 | ALPL (0.40) | — | |
| SCHEMBL3294940 | 0.66 | — | — | |
| SCHEMBL2374927 | 0.64 | L3MBTL1 (0.58) | — | |
| SCHEMBL9203533 | 0.64 | — | — | |
| SCHEMBL20046176 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204378-B1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2019-07-10 | — | — | EP | disclosed |