Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 5/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867210 | 0.78 | AXL (0.53) | ALPLAXLKEAP1NPC1MAPT | |
| SCHEMBL6286060 | 0.71 | METAP2 (0.40) | NPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL31371362 | 0.68 | TRPM8 (0.53) | ALPLNPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9530403 | 0.68 | MPO (0.39) | AXLKEAP1SMN1; SMN2MAPK1KDM4E | |
| SCHEMBL3846622 | 0.67 | ALPL (0.35) | ALPLTGFBR1CYP3A4CYP2C8NPC1 | |
| SCHEMBL2374927 | 0.67 | L3MBTL1 (0.58) | ALOX15RAB9ACYP1A2POLBGAA | |
| SCHEMBL9529749 | 0.67 | GRM5 (0.33) | TGFBR1CYP3A4CYP2C8MAPT | |
| SCHEMBL31371407 | 0.66 | ALPL (0.51) | ALPLNPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL22415326 | 0.66 | HPGD (0.50) | CYP3A4NPC1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9766850 | 0.65 | CA9 (0.52) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |