Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252186 | 0.88 | TSHR (0.69) | TSHRSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL732456 | 0.83 | NAMPT (0.57) | CA1CA2MAPT | |
| SCHEMBL694352 | 0.81 | NPC1 (0.53) | TSHRSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL3598004 | 0.81 | TSHR (0.61) | TSHRSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL13477518 | 0.81 | KMT2A (0.61) | SMN1; SMN2NPC1ALDH1A1RAB9APTPN1 | |
| SCHEMBL10117993 | 0.81 | TSHR (0.61) | TSHRSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL3598006 | 0.81 | TSHR (0.61) | TSHRSMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL22837260 | 0.80 | ALDH1A1 (0.59) | TSHRSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL3006709 | 0.79 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL2721206 | 0.79 | ALDH1A1 (0.65) | TSHRSMN1; SMN2NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |