Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306213 | 0.87 | KDM4E (0.45) | SLC9A1PDE10ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL18487252 | 0.79 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL1011902 | 0.78 | ALDH1A1 (0.53) | PDE10ATXNRD1TXNRD3TXNRD2MEN1 | |
| SCHEMBL12404118 | 0.77 | PDE10A (0.43) | SLC9A1PDE10ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL10426653 | 0.76 | PDE10A (0.49) | PDE10ATXNRD1TXNRD3TXNRD2NPC1 | |
| SCHEMBL18742358 | 0.76 | LIMK1 (0.44) | PDE10AMEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL4920165 | 0.76 | ALDH1A1 (0.50) | PDE10ATXNRD1TXNRD3TXNRD2NPC1 | |
| SCHEMBL1039915 | 0.76 | PDPK1 (0.59) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL31122218 | 0.76 | PDE10A (0.49) | PDE10ATXNRD1TXNRD3TXNRD2NPC1 | |
| SCHEMBL15880740 | 0.75 | TDP1 (0.48) | PDE10ATXNRD1TXNRD3TXNRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949970-B2 | Synthesis of new benzothiazole derivatives as potential anti-tubercular agents | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20160175303-A1 | SYNTHESIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-06-23 | — | — | US | disclosed |
| US-9273039-B2 | Synthesis of new benzothiazole derivatives as potential anti-tubercular agents | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-03-01 | — | — | US | disclosed |
| CN-104628671-A | Nitrobenzothiazole carboxylic acid amide compounds containing phenylamidine structures and application | FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-104628671-A | Nitrobenzothiazole carboxylic acid amide compounds containing phenylamidine structures and application | FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-05-20 | — | — | CN | disclosed |
| US-20120095021-A1 | SYNTHSIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175303-A1 | SYNTHESIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | TST, TBCA, SDHA | SLC9A1 4294/4885PDE10A 1992/4885TXNRD1 470/4885 |
| US-20120095021-A1 | SYNTHSIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | TST, SDHB, SDHA | SLC9A1 3253/4885PDE10A 3999/4885TXNRD1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.