Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19295807 | 0.79 | ALDH1A1 (0.36) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL18462938 | 0.79 | ALDH1A1 (0.36) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL14410302 | 0.78 | ALDH1A1 (0.39) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL15381964 | 0.76 | DPP4 (0.40) | MMP2ECE1ALDH1A1LMNAMAPT | |
| SCHEMBL15381963 | 0.75 | TERT (0.43) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL24476459 | 0.74 | CTSS (0.36) | ECE1ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL25939115 | 0.73 | TNF (0.33) | TNFMMP1MMP2MMP3ADAM17 | |
| SCHEMBL25939110 | 0.73 | TNF (0.33) | TNFMMP1MMP2MMP3ADAM17 | |
| SCHEMBL10208283 | 0.72 | POLB (0.38) | TNFMMP1MMP2MMP3ADAM17 | |
| SCHEMBL23643337 | 0.67 | RECQL (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |