Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21901011 | 0.89 | ALDH1A1 (0.49) | TDP1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL10904247 | 0.87 | KMT2A (0.53) | TDP1ALDH1A1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL10905007 | 0.85 | KMT2A (0.52) | TDP1ALDH1A1KMT2APOLBMAPT | |
| Hydrochloric Acid SCHEMBL10904248 | 0.85 | KMT2A (0.52) | TDP1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL21155014 | 0.83 | ALDH1A1 (0.46) | TDP1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL8519008 | 0.81 | NAAA (0.57) | TDP1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL14974133 | 0.81 | POLB (0.47) | TDP1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL8375337 | 0.80 | KMT2A (0.50) | TDP1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL20093506 | 0.80 | HTT (0.46) | TDP1ALDH1A1KMT2APOLBMAPT | |
| SCHEMBL18196617 | 0.79 | HDAC3 (0.54) | TDP1ALDH1A1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023065610-A1 | PREPARATION METHOD FOR HALOFUGINONE INTERMEDIATE TRANS-N-BENZYLOXYCARBONYL-(3-HYDROXY-2-PIPERIDINYL)-2-ACETONE | 诚达药业股份有限公司 | 2023-04-27 | — | — | WO | disclosed |