Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | PLK4 | O00444 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | PAK4 | O96013 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666776 | 0.83 | SLC6A3 (0.48) | ALDH1A1MEN1KMT2AL3MBTL1SLC6A3 | |
| SCHEMBL232284 | 0.81 | HTT (0.50) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6216437 | 0.78 | NSD2 (0.44) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8533409 | 0.78 | CLCN2 (0.46) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11750773 | 0.78 | SIRT1 (0.61) | HPGDALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8612788 | 0.76 | SLC6A3 (0.49) | HPGDALDH1A1L3MBTL1PLK1SLC6A3 | |
| SCHEMBL18664358 | 0.75 | RAB9A (0.56) | HPGDALDH1A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL618503 | 0.73 | SLC6A3 (0.54) | HPGDKMT2AL3MBTL1PLK1SLC6A3 | |
| SCHEMBL22579323 | 0.72 | SLC6A3 (0.45) | PLK1SLC6A3SLC6A2SLC6A4KDR | |
| SCHEMBL11442238 | 0.72 | SIRT1 (0.46) | HPGDALDH1A1KMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116316-B1 | HEPATITIS B CORE PROTEIN ALLOSTERIC MODULATORS | UNIV INDIANA RES & TECH CORP (US) | 2019-07-10 | — | — | EP | disclosed |