Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155988 | 0.87 | FDPS (0.54) | TOP2AALDH1A1FDPSKDM4ENFE2L2 | |
| SCHEMBL20906894 | 0.85 | FDPS (0.58) | TOP2AALDH1A1HPGDFDPSKDM4E | |
| SCHEMBL18569889 | 0.82 | NFE2L2 (0.61) | TOP2AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL21155675 | 0.81 | KDM4E (0.55) | TOP2AALDH1A1FDPSKDM4ENFE2L2 | |
| SCHEMBL21155973 | 0.81 | FDPS (0.54) | TOP2AALDH1A1HPGDFDPSKDM4E | |
| SCHEMBL21156516 | 0.81 | NFE2L2 (0.60) | TOP2AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL24080302 | 0.81 | FDPS (0.48) | KMT2AMEN1ALDH1A1HPGDFDPS | |
| SCHEMBL19415798 | 0.81 | NFE2L2 (0.61) | TOP2AKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL24266526 | 0.80 | FDPS (0.55) | TOP2AALDH1A1HPGDFDPSKDM4E | |
| SCHEMBL24080309 | 0.79 | FDPS (0.59) | TOP2AALDH1A1HPGDFDPSKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135110-B1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | TRIOPTOTEC GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |