Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 2/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974158 | 0.88 | NFE2L2 (0.62) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL24080302 | 0.86 | FDPS (0.48) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL16621582 | 0.85 | NFE2L2 (0.59) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL9974196 | 0.85 | APP (0.61) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL9974139 | 0.85 | NFE2L2 (0.66) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL18570134 | 0.84 | NFE2L2 (0.62) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL18079046 | 0.84 | APP (0.60) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL21156516 | 0.83 | NFE2L2 (0.60) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL9974198 | 0.83 | TOP2A (0.61) | NFE2L2KDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL21155729 | 0.82 | TOP2A (0.49) | NFE2L2KDM4EALDH1A1HPGDPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220054671-A1 | 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF | UNIVERSITÄTSKLINIKUM REGENSBURG (DE) | 2022-02-24 | — | — | US | disclosed |
| US-11191855-B2 | 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof | UNIVERSITÄTSKLINIKUM REGENSBURG (DE) | 2021-12-07 | — | — | US | disclosed |
| EP-3135110-B1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | TRIOPTOTEC GMBH (DE) | 2019-07-10 | — | — | EP | disclosed |
| US-20190111168-A1 | PHOTOSENSITIZER DISPERSION, AND USE THEREOF | UNIVERSITÄT REGENSBURG (DE) | 2019-04-18 | — | — | US | disclosed |
| EP-3135110-A1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | Universitätsklinikum Regensburg (DE) | 2017-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220054671-A1 | 1,7-DIARYL-1,6-HEPTADIENE-3,5-DIONE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF | DHPS, SQLE, CYP51A1 | NFE2L2 1038/4885KDM4E 3887/4885ALDH1A1 103/4885 |
| US-20190111168-A1 | PHOTOSENSITIZER DISPERSION, AND USE THEREOF | PPOX, ALAD, PPID | NFE2L2 513/4885KDM4E 2638/4885ALDH1A1 207/4885 |
| US-11191855-B2 | 1,7-diaryl-1,6-heptadiene-3,5-dione derivatives, methods for the production and use thereof | DHPS, SQLE, CYP51A1 | NFE2L2 1038/4885KDM4E 3887/4885ALDH1A1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.