Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21157861 | 0.87 | GPR55 (0.48) | TAAR1DAOCHRM2CHRM1CHRM3 | |
| SCHEMBL21157986 | 0.82 | RAB9A (0.48) | TAAR1DAONR3C2NR1H3ALDH1A1 | |
| SCHEMBL21156703 | 0.79 | CYP19A1 (0.49) | DAONR1H3NR1H2AOC3ALDH1A1 | |
| SCHEMBL30866423 | 0.79 | CYP19A1 (0.49) | DAONR1H3NR1H2AOC3ALDH1A1 | |
| SCHEMBL21157246 | 0.78 | TAAR1 (0.45) | TAAR1ALDH1A1 | |
| SCHEMBL22554350 | 0.77 | NPC1 (0.49) | DAOALDH1A1 | |
| SCHEMBL30080050 | 0.76 | TAAR1 (0.77) | TAAR1DAOCHRM2CHRM1CHRM3 | |
| SCHEMBL723511 | 0.76 | TAAR1 (0.77) | TAAR1DAOCHRM2CHRM1CHRM3 | |
| SCHEMBL21122490 | 0.76 | PTPN1 (0.54) | TAAR1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL21121172 | 0.76 | POLB (0.51) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587239-B | Method for producing lactam compound and lactam compound produced by the method | 基础科学研究院 | 2024-04-02 | — | — | CN | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | INSTITUTE FOR BASIC SCIENCE (KR) | 2021-06-29 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | INSTITUTE FOR BASIC SCIENCE (KR) | 2020-10-22 | — | — | US | disclosed |
| CN-111587239-A | Method for producing lactam compound and lactam compound produced by same | 基础科学研究院 | 2020-08-25 | — | — | CN | disclosed |
| WO-2019135604-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | 기초과학연구원 | 2019-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331871-A1 | METHOD FOR PRODUCING LACTAM COMPOUND, AND LACTAM COMPOUND PRODUCED THEREBY | SQLE, COASY, DHPS | TAAR1 4408/4885DAO 7/4885CHRM2 4413/4885 |
| US-11046661-B2 | Method for producing lactam compound, and lactam compound produced thereby | SQLE, COASY, DHPS | TAAR1 4408/4885DAO 7/4885CHRM2 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.