Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964770 | 0.88 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAASMN1; SMN2GLA | |
| SCHEMBL19964768 | 0.79 | BAZ2B (0.43) | ALDH1A1KDM4EGAASMN1; SMN2GLA | |
| SCHEMBL21157314 | 0.78 | EED (0.49) | PKM | |
| SCHEMBL19964390 | 0.76 | EED (0.39) | ALDH1A1KDM4EGAASMN1; SMN2TSHR | |
| SCHEMBL21157315 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAATDP1HSD17B10 | |
| SCHEMBL21157283 | 0.73 | ALOX15 (0.41) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TSHR | |
| SCHEMBL21113322 | 0.73 | L3MBTL3 (0.33) | KDM4EL3MBTL1MAPT | |
| SCHEMBL21156554 | 0.72 | HRH3 (0.39) | ALDH1A1KDM4ESMN1; SMN2TSHRRAB9A | |
| SCHEMBL21251244 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2TSHRPKM | |
| SCHEMBL21156531 | 0.71 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | HAIHE BIOPHARMA CO. LTD. (CN) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211010-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | EZH2, IKZF2, SUZ12 | ALDH1A1 2816/4885KDM4E 52/4885GAA 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.