Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.39 |
| ▸ | PDE4A | P27815 | 7/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158773 | 0.91 | PDE4D (0.50) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL21158910 | 0.89 | PDE4D (0.48) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL21158931 | 0.86 | PDE4D (0.35) | STING1PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL21158909 | 0.84 | IRAK4 (0.38) | STING1PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL28912725 | 0.84 | MAPT (0.44) | STING1PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL21158729 | 0.82 | TSHR (0.35) | STING1TSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL19437435 | 0.80 | ALDH1A1 (0.46) | PDE4DPDE4BPDE4APDE4CTSHR | |
| SCHEMBL22121045 | 0.78 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21158654 | 0.78 | PARP15 (0.43) | PDE4DPDE4BPDE4APDE4CTSHR | |
| SCHEMBL28552449 | 0.77 | PDE4D (0.47) | PDE4DPDE4BPDE4APDE4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2019134707-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |