Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158654 | 0.86 | PARP15 (0.43) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28553322 | 0.85 | KMT2A (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL21158909 | 0.83 | IRAK4 (0.38) | SMN1; SMN2TSHRIRAK4ALDH1A1MEN1 | |
| SCHEMBL22121045 | 0.80 | TSHR (0.43) | SMN1; SMN2TSHRALDH1A1MAPTMEN1 | |
| SCHEMBL21158910 | 0.79 | PDE4D (0.48) | — | |
| SCHEMBL21158773 | 0.77 | PDE4D (0.50) | — | |
| SCHEMBL21158729 | 0.77 | TSHR (0.35) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL19437435 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22135950 | 0.77 | TSHR (0.40) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL21158643 | 0.76 | STING1 (0.42) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016021-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2019134707-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2019-07-11 | — | — | WO | disclosed |