Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22991569 | 0.82 | TTR (0.61) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL10877649 | 0.79 | TTR (0.56) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL7927726 | 0.79 | GABRA1 (0.78) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL22280538 | 0.78 | TTR (0.42) | TTRGABRA1GABRB1GABRB2ERN1 | |
| Triiodophenol SCHEMBL338137 | 0.76 | TTR (1.00) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL26696417 | 0.76 | TTR (0.58) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL25836502 | 0.74 | TTR (0.56) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL22991642 | 0.73 | TTR (0.54) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL26295914 | 0.73 | TTR (0.54) | TTRGABRA1GABRB1GABRB2ERN1 | |
| SCHEMBL21241704 | 0.70 | TTR (0.50) | TTRGABRA1GABRB1GABRB2ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135975-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC. (US) | 2019-07-11 | — | — | WO | disclosed |