SCHEMBL22280538

SCHEMBL22280538

OC(O)c1cc(I)cc(I)c1I

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.42
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRB2 P47870 1/20 0.39
ERN1 O75460 1/20 0.31
TPMT P51580 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21159415 0.78 TTR (0.59) TTRGABRA1GABRB1GABRB2ERN1
SCHEMBL7152837 0.78 ADRA2A (0.38) TTRGABRA1GABRB1GABRB2
SCHEMBL27106901 0.76 TTR (0.34) TTRGABRA1GABRB1GABRB2ERN1
SCHEMBL21263766 0.75 GABRA1 (0.56) TTRGABRA1GABRB1GABRB2
SCHEMBL17161274 0.71 GABRA1 (0.41) TTRGABRA1GABRB1GABRB2
SCHEMBL22403150 0.71 TTR (0.34) TTRGABRA1GABRB1GABRB2
SCHEMBL24218923 0.70 TTR (0.48) TTRGABRA1GABRB1GABRB2ERN1
SCHEMBL25479340 0.66
SCHEMBL22991569 0.65 TTR (0.61) TTRGABRA1GABRB1GABRB2ERN1
SCHEMBL4961622 0.65 TTR (0.55) TTRGABRA1GABRB1GABRB2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
US-20220026803-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-01-27 US disclosed
US-20200241418-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-30 US disclosed