Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.78 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.78 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.78 |
| ▸ | TTR | P02766 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163939 | 0.88 | GABRA1 (1.00) | GABRA1GABRB1GABRB2TTRCA1 | |
| SCHEMBL22991569 | 0.84 | TTR (0.61) | GABRA1GABRB1GABRB2TTRCA1 | |
| SCHEMBL4862739 | 0.80 | GABRA1 (0.63) | GABRA1GABRB1GABRB2TTRCA1 | |
| Triiodophenol SCHEMBL338137 | 0.80 | TTR (1.00) | GABRA1GABRB1GABRB2TTRCA1 | |
| SCHEMBL26295914 | 0.79 | TTR (0.54) | GABRA1GABRB1GABRB2TTRCA1 | |
| SCHEMBL22991642 | 0.79 | TTR (0.54) | GABRA1GABRB1GABRB2TTRCA1 | |
| SCHEMBL21159415 | 0.79 | TTR (0.59) | GABRA1GABRB1GABRB2TTRERN1 | |
| SCHEMBL24477885 | 0.78 | GABRA1 (0.72) | GABRA1GABRB1GABRB2TTRCA1 | |
| SCHEMBL26696417 | 0.78 | TTR (0.58) | GABRA1GABRB1GABRB2TTRERN1 | |
| SCHEMBL817922 | 0.78 | GABRA1 (0.72) | GABRA1GABRB1GABRB2TTRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230101-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTIONS AND OTHER INFECTIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-29 | — | — | US | disclosed |
| EP-0707849-B1 | USE OF DERIVATIVES OF 2,4-DISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S L (ES) | 2001-12-19 | — | — | EP | disclosed |
| EP-0707849-A1 | USE OF DERIVATIVES OF 2,4-BISUBSTITUTED PHENOLS AS 5-LIPOXIGENASE INHIBITORS | BOBEL246 S.L. (ES) | 1996-04-24 | — | — | EP | disclosed |
| US-5166171-A | Compounds for treatment of artheriosclerosis and hypercholesterolemia | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230101-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTIONS AND OTHER INFECTIONS | EIF2AK2, HAVCR2, MAVS | GABRA1 3878/4885GABRB1 3671/4885GABRB2 3657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.