Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.35 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | BLVRB | P30043 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349821 | 0.75 | HMGB1 (0.53) | AKR1C2AKR1C1HMGB1CXCL12AKR1C4 | |
| SCHEMBL29451088 | 0.73 | AKR1C2 (0.40) | PTPN1AKR1C2AKR1C1HMGB1CXCL12 | |
| SCHEMBL21122016 | 0.73 | AKR1C2 (0.40) | PTPN1AKR1C2AKR1C1HMGB1CXCL12 | |
| SCHEMBL9349088 | 0.72 | ALDH1A1 (0.42) | PTPN1PTPN6PTPN2AKR1C2AKR1C1 | |
| SCHEMBL11694249 | 0.69 | AKR1C2 (0.48) | PTPN1PTPN6PTPN2AKR1C2AKR1C1 | |
| SCHEMBL11130591 | 0.68 | ALDH1A1 (0.53) | PTPN1HMGB1HNF4AMEN1KMT2A | |
| SCHEMBL11130587 | 0.68 | ALDH1A1 (0.53) | PTPN1HMGB1HNF4AMEN1KMT2A | |
| SCHEMBL29030423 | 0.65 | ALDH1A1 (0.52) | PTPN1MEN1KMT2ATHRBCYP2C9 | |
| SCHEMBL2536166 | 0.64 | HNF4A (0.62) | PTPN1PTPN6PTPN2HNF4AMEN1 | |
| SCHEMBL28533609 | 0.64 | AKR1C2 (0.41) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019135975-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC. (US) | 2019-07-11 | — | — | WO | disclosed |