Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 6/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 6/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | BLVRB | P30043 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ATIC | P31939 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29451088 | 1.00 | AKR1C2 (0.40) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL9349821 | 0.79 | HMGB1 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL2810137 | 0.79 | CYP1A1 (0.34) | — | |
| SCHEMBL9349088 | 0.77 | ALDH1A1 (0.42) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL689828 | 0.74 | HNF4A (0.41) | AKR1C2AKR1C1AKR1C3MEN1KMT2A | |
| SCHEMBL689510 | 0.74 | CYP1A2 (0.39) | MEN1KMT2AHTTPDE4ABLVRB | |
| SCHEMBL4959352 | 0.73 | XDH (0.41) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL21159417 | 0.73 | PTPN1 (0.36) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL2536166 | 0.71 | HNF4A (0.62) | MEN1KMT2AHTTPDE4ABLVRB | |
| SCHEMBL541999 | 0.69 | HNF4A (0.43) | MEN1KMT2AHNF4AHSD17B10CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137293-A2 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | ROCHE SEQUENCING SOLUTIONS INC (US) | 2025-03-06 | — | — | US | disclosed |
| US-11970731-B2 | Enhancement of nucleic acid polymerization by aromatic compounds | Roche Sequencing Solutions, Inc. (US) | 2024-04-30 | — | — | US | disclosed |
| EP-3735409-B1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC (US) | 2023-06-21 | — | — | EP | disclosed |
| EP-3735409-B1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC (US) | 2023-06-21 | — | — | EP | disclosed |
| EP-3994262-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Stratos Genomics Inc. (US) | 2022-05-11 | — | — | EP | disclosed |
| US-20220112548-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2022-04-14 | — | — | US | disclosed |
| CN-114144520-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2022-03-04 | — | — | CN | disclosed |
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2021-03-04 | — | — | US | disclosed |
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Roche Sequencing Solutions, Inc. | 2021-03-04 | — | — | US | disclosed |
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020263703-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| EP-3735409-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | Stratos Genomics Inc. (US) | 2020-11-11 | — | — | EP | disclosed |
| CN-111771001-A | Enhanced nucleic acid polymerization by aromatic compounds | 斯特拉托斯基因公司 | 2020-10-13 | — | — | CN | disclosed |
| WO-2019135975-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | STRATOS GENOMICS INC. (US) | 2019-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210062251-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | POLN, POLB, POLRMT | AKR1C2 2097/4885AKR1C1 2290/4885AKR1C4 2052/4885 |
| US-11970731-B2 | Enhancement of nucleic acid polymerization by aromatic compounds | POLN, POLB, POLRMT | AKR1C2 2097/4885AKR1C1 2290/4885AKR1C4 2052/4885 |
| US-20250075265-A1 | ENHANCEMENT OF NUCLEIC ACID POLYMERIZATION BY AROMATIC COMPOUNDS | POLN, POLB, POLRMT | AKR1C2 2097/4885AKR1C1 2290/4885AKR1C4 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.