Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 3/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | BLVRB | P30043 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615611 | 0.84 | ALDH1A1 (0.55) | HNF4ACA1CA2CA12CA7 | |
| SCHEMBL541999 | 0.83 | HNF4A (0.43) | HNF4ACA1CA2PTGS2CA12 | |
| Hydrochloric Acid SCHEMBL6732842 | 0.82 | HNF4A (0.42) | HNF4ACA1CA2PTGS2CA12 | |
| SCHEMBL2747715 | 0.82 | F2 (0.44) | HNF4ACA1CA2PTGS2ALDH1A1 | |
| SCHEMBL131551 | 0.80 | HNF4A (0.62) | HNF4ACA1CA2PTGS2CA12 | |
| SCHEMBL30902488 | 0.80 | HNF4A (0.62) | HNF4ACA1CA2PTGS2CA12 | |
| SCHEMBL689828 | 0.80 | HNF4A (0.41) | HNF4APTGS2MEN1KMT2AKDR | |
| SCHEMBL30828728 | 0.79 | HNF4A (0.61) | HNF4ACA1CA2PTGS2CA12 | |
| SCHEMBL1783561 | 0.78 | ALDH1A1 (0.57) | HNF4AMEN1KMT2ATDP1KDM4E | |
| SCHEMBL20564443 | 0.78 | CYP3A4 (0.40) | HNF4APTGS2KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394980-B1 | AROMATIC AMINO COMPOUND MANUFACTURING METHOD | HODOGAYA CHEMICAL CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| US-9238624-B2 | Method of producing aromatic amino compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-01-19 | — | — | US | disclosed |
| US-20140163232-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| US-8735626-B2 | Method of producing aromatic amino compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-27 | — | — | US | disclosed |
| EP-2394980-A1 | AROMATIC AMINO COMPOUND MANUFACTURING METHOD | Hodogaya Chemical Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| CN-102239133-A | Aromatic amino compound manufacturing method | HODOGAYA CHEMICAL CO LTD | 2011-11-09 | — | — | CN | disclosed |
| US-20110257404-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
| US-7833335-B2 | Ink-jet ink sets | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2010-11-16 | — | — | US | disclosed |
| US-20080252681-A1 | Ink-jet ink sets | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163232-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | DDC, AOC2, AOC3 | HNF4A 2672/4885CA1 665/4885CA2 1239/4885 |
| US-20110257404-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | AOC2, AOC3, DDC | HNF4A 3115/4885CA1 1873/4885CA2 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.