Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443667 | 0.78 | HRH3 (0.45) | HPGDTP53HRH3ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31587507 | 0.76 | HRH3 (0.44) | HPGDTP53HRH3LMNAALDH1A1 | |
| SCHEMBL188044 | 0.69 | ALDH1A1 (0.41) | HPGDHRH3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3164216 | 0.64 | ALDH1A1 (0.52) | HPGDTP53HRH3ALDH1A1MAPT | |
| SCHEMBL13907288 | 0.63 | HTR6 (0.42) | NPSR1 | |
| SCHEMBL3168328 | 0.62 | L3MBTL1 (0.54) | HPGDMAPK1HRH3LMNAALDH1A1 | |
| SCHEMBL4613110 | 0.62 | MEN1 (0.39) | HRH3LMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL29995391 | 0.62 | L3MBTL1 (0.54) | HPGDMAPK1HRH3LMNAALDH1A1 | |
| SCHEMBL4750348 | 0.61 | HRH3 (0.46) | HPGDHRH3ALDH1A1NPSR1MAPT | |
| SCHEMBL22031681 | 0.61 | HRH3 (0.39) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136147-A1 | TOLL-LIKE RECEPTOR SIGNALING INHIBITORS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-07-11 | — | — | WO | disclosed |