Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190669 | 0.78 | PIK3CD (0.37) | ALDH1A1ADH1BADH1CADH1AALOX5 | |
| SCHEMBL17471262 | 0.76 | TRPM8 (0.33) | ALDH1A1ADH1BADH1CADH1AALOX5 | |
| SCHEMBL15116483 | 0.76 | ALDH1A1 (0.34) | ALDH1A1ADH1BADH1CADH1AALOX5 | |
| SCHEMBL17190681 | 0.74 | DPP4 (0.32) | ALDH1A1 | |
| SCHEMBL15114445 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL15125229 | 0.73 | MAPT (0.30) | ALDH1A1 | |
| SCHEMBL20054333 | 0.73 | ALOX5 (0.36) | ALDH1A1ALOX5 | |
| SCHEMBL19027646 | 0.73 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL15113695 | 0.73 | TRPM8 (0.31) | ALDH1A1TRPM8 | |
| SCHEMBL17190680 | 0.73 | GAA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190211033-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211033-A1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | CFD, F12, F3 | ALDH1A1 1682/4885ADH1B 914/4885ADH1C 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.