Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.34 |
| ▸ | TEK | Q02763 | 4/20 | 0.34 |
| ▸ | DLK1 | P80370 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160642 | 0.67 | PARP1 (0.58) | PARP1CDK4CCND1 | |
| SCHEMBL21160074 | 0.67 | PARP1 (0.48) | PARP1 | |
| SCHEMBL21155204 | 0.66 | PARP1 (0.56) | PARP1CDK4CCND1 | |
| SCHEMBL12256417 | 0.55 | PARP1 (1.00) | PARP1 | |
| SCHEMBL29435084 | 0.55 | PARP1 (1.00) | PARP1 | |
| SCHEMBL13164131 | 0.53 | CA12 (0.43) | — | |
| SCHEMBL6754538 | 0.51 | HTR6 (0.45) | — | |
| SCHEMBL10328 | 0.50 | BRD4 (0.51) | — | |
| SCHEMBL6824387 | 0.49 | CA1 (0.53) | — | |
| SCHEMBL20946442 | 0.49 | MET (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136298-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATMENT OF DISEASES INVOLVING ACIDIC OR HYPOXIC DISEASED TISSUES | Cybrexa, Inc. (US) | 2019-07-11 | — | — | WO | disclosed |